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Clostridium species are readily found inhabiting soils and intestinal tracts. Clostridium species are also a normal inhabitant of the healthy lower reproductive tract of females. [14] The main species responsible for disease in humans are: [15] Clostridium botulinum can produce botulinum toxin in food or wounds and can cause botulism.
[2] [4] Global rates of disease increased between 2001 and 2016. [2] [11] C. difficile infections occur more often in women than men. [2] The bacterium was discovered in 1935 and found to be disease-causing in 1978. [11] Attributable costs for Clostridioides difficile infection in hospitalized adults range from $4500 to $15,000. [12]
Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]
Roughly 10 million cases of foodborne illness each year in the U.S. are caused by six pathogens — salmonella, listeria monocytogenes, campylobacter, clostridium perfringens, shiga toxin ...
Clostridium perfringens is a common cause of food poisoning in the United States. C. perfringens produces spores, and when these spores are consumed, they produce a toxin that causes diarrhea. Foods cooked in large batches and held at unsafe temperatures (between 40°F and 140°F) are the source of C. perfringens food poisoning outbreaks.
Clostridium botulinum is a bacterium that produces botulinum toxin, the neurotoxin that causes botulism, says Dr. Daniel Kuritzkes, Chief of the Division of Infectious Diseases at Brigham and ...
Overuse of antibiotics can cause imbalance of the gut microbiome, leading to overgrowth of the species Clostridioides difficile causing a serious infection (CDI). [12] Effects of this infection include severe diarrhea and the severity of many bowel related diseases is also increased as a result of the infection.
Gas gangrene (also known as clostridial myonecrosis [1]) is a bacterial infection that produces tissue gas in gangrene. This deadly form of gangrene usually is caused by Clostridium perfringens bacteria. About 1,000 cases of gas gangrene are reported yearly in the United States. [2]