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The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection.
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
It occurs primarily in elderly adults, far less frequency in younger adults, and rarely in children. Elderly adults present with B symptoms (i.e. fever, night sweats, and weight loss), swollen lymph nodes, and symptoms due to malignant cell infiltrations into the upper gastrointestinal tract, lungs, upper airways, and/or other organs. Younger ...
Monocytosis often occurs during chronic inflammation.Diseases that produce such a chronic inflammatory state: [citation needed] Infections: tuberculosis, brucellosis, listeriosis, subacute bacterial endocarditis, syphilis, and other viral infections and many protozoal and rickettsial infections (e.g. kala azar, malaria, Rocky Mountain spotted fever).
Epstein Barr Virus (EBV) causes the illness referred to as Mononucleosis. In the infectious stage of this illness, individuals will have Epstein Barr viral capsid antigens (EBV-VCA) in their mouth and blood. [1] [2] The viral capsid of a virus is the complex of proteins that surrounds the genetic material inside the virus. Epstein Barr virus ...
The CDC said 1.7% of adults ages 65 to 74 reported a dementia diagnosis, a rate that increased with age. For those ages 75 to 84, the reported dementia rate was 5.7%
Epstein–Barr virus infectious mononucleosis (Mono) Diagnostic modalities for infectious mononucleosis include: Person's age, with highest risk at 10 to 30 years. Medical history, such as close contact with other people with infectious mononucleosis; Physical examination, including palpation of any enlarged lymph nodes in the neck, or enlarged ...