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Steatohepatitis is a type of fatty liver disease, characterized by inflammation of the liver with concurrent fat accumulation in liver. Mere deposition of fat in the liver is termed steatosis , and together these constitute fatty liver changes.
For people with NASH and end-stage liver disease, liver failure, or liver cancer, liver transplantation is an accepted procedure according to the EASL. [16] People with NASH cirrhosis NASH who are being considered for a liver transplant warrant systematic evaluation for cardiovascular diseases (whether the symptoms are apparent or not). [5]
Micrograph of inflamed fatty liver (steatohepatitis) Severe fatty liver is sometimes accompanied by inflammation, a situation referred to as steatohepatitis. Progression to alcoholic steatohepatitis (ASH) or non-alcoholic steatohepatitis (NASH) depends on the persistence or severity of the inciting cause.
Nonalcoholic steatohepatitis (NASH). With this type of fatty liver disease, you’ll have fat in your liver, inflammation, and liver cell damage. This can lead to cirrhosis (liver scarring) and ...
On Tuesday, Viking Therapeutics, Inc. (NASDAQ:VKTX) highlighted the final results from its VOYAGE Phase 2b trial of VK2809 in patients with biopsy-confirmed non-alcoholic steatohepatitis (NASH ...
NASH, which can progress to liver failure, affects 5% of the U.S. population, but development of a drug for the disease has seen numerous clinical failures, most recently by Intercept Pharmaceuticals.
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