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Mitosis in the animal cell cycle (phases ordered counter-clockwise). Mitosis divides the chromosomes in a cell nucleus. Onion cells in different phases of the cell cycle enlarged 800 diameters. Mitosis (/ maɪˈtoʊsɪs /) is a part of the cell cycle in which replicated chromosomes are separated into two new nuclei.
In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. It is referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process ...
A full set of sister chromatids is created during the synthesis (S) phase of interphase, when all the chromosomes in a cell are replicated. The two sister chromatids are separated from each other into two different cells during mitosis or during the second division of meiosis. Compare sister chromatids to homologous chromosomes, which are the ...
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Kinetochore. A kinetochore (/ kɪˈnɛtəkɔːr /, /- ˈniːtəkɔːr /) is a disc-shaped protein structure associated with duplicated chromatids in eukaryotic cells where the spindle fibers attach during cell division to pull sister chromatids apart. [1] The kinetochore assembles on the centromere and links the chromosome to microtubule ...
Scheme showing cell cycle progression between prometaphase and anaphase. The spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic checkpoint, is a cell cycle checkpoint during metaphase of mitosis or meiosis that prevents the separation of the ...
Prophase is the first stage of mitosis in animal cells, and the second stage of mitosis in plant cells. [ 10 ] At the start of prophase there are two identical copies of each chromosome in the cell due to replication in interphase. These copies are referred to as sister chromatids and are attached by DNA element called the centromere. [ 11 ]
Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1). [ 1 ][ 2 ] Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts. [ 3 ]