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Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
The process is highly regulated by cell adhesion molecules, particularly, the addressin also known as MADCAM1. This antigen is known for its role in tissue-specific adhesion of lymphocytes to high endothelium venules. [23] Through these interactions they play a crucial role in orchestrating circulating lymphocytes.
This allows for homophilic cell–cell adhesion. [18] The β-catenin–α-catenin linked complex at the adherens junctions allows for the formation of a dynamic link to the actin cytoskeleton. [19] Integrins act as adhesion receptors, transporting signals across the plasma membrane in multiple directions. These molecules are an invaluable part ...
Note 1: Adhesion requires energy that can come from chemical and/or physical linkages, the latter being reversible when enough energy is applied. Note 2: In biology, adhesion reflects the behavior of cells shortly after contact to the surface. Note 3: In surgery, adhesion is used when two tissues fuse unexpectedly. [1]
[5] Synaptic signaling, an integral part of nervous system activity, occurs between neurons and target cells. These target cells can also be neurons or other cell types (i.e. muscle or gland cells). Protocadherins, a member of the cadherin family, mediate the adhesion of neurons to their target cells at synapses otherwise known as synaptic ...
As the similarities between the adhesive and the substrate increase, so does the degree of mucoadhesion. [5] The bond strength increases with the degree of penetration, increasing the adhesion strength. [11] The penetration rate is determined by the diffusion coefficient, the degree of flexibility of the adsorbate chains, mobility and contact ...
Adsorption is the adhesion [1] of atoms, ions or molecules from a gas, liquid or dissolved solid to a surface. [2] This process creates a film of the adsorbate on the surface of the adsorbent. This process differs from absorption, in which a fluid (the absorbate) is dissolved by or permeates a liquid or solid (the absorbent). [3]
Escherichia coli FimH provides an example of conformation specific immune response which enhances impact on the protein. [19] By studying this particular adhesion, researchers hope to develop adhesion-specific vaccines which may serve as a model for antibody-mediation of pathogen adhesion.