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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [ 2 ]
The recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir taken twice a day. In addition to preventing outbreaks, these medications greatly reduce the chance of infecting someone while the patient is not having an outbreak. [citation needed]
Valganciclovir, sold under the brand name Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant. [3]
Valaciclovir (Valtrex) [20] Herpes Simplex/Zoster Valganciclovir (Valcyte) [21] Cytomegalovirus (CMV) Vicriviroc: HIV-1: Schering-Plough pyrimidine CCR5 entry inhibitor Vidarabine: Herpes Simplex, Varicella Zoster: Zalcitabine: HIV Zanamivir (Relenza) [22] Influenza A, Influenza B Zidovudine: HIV [23] Antiretroviral
However, this effect has not been clinically established and more studies need to be done to evaluate the true potential of this synergy. [ 37 ] Probenecid : Reports of increased half-life of aciclovir, as well as decreased urinary excretion and renal clearance have been shown in studies where probenecid is given simultaneously with aciclovir.
HIV is an RNA virus, so it can not be integrated into the DNA in the nucleus of the human cell unless it is first "reverse" transcribed into DNA. Since the conversion of RNA to DNA is not naturally done in the mammalian cell, it is performed by a viral protein, reverse transcriptase, which makes it a selective target for inhibition. NRTIs are ...
The bottom line represents benzodiazepine deaths that did not involve opioids. [1] Benzodiazepines have a wide therapeutic index and taken alone in overdose rarely cause severe complications or fatalities. [13] [25] More often than not, a patient who inadvertently takes more than the prescribed dose will simply feel drowsy and fall asleep for a ...
Brivudine is used for the treatment of herpes zoster in adult patients. It is taken orally once daily, in contrast to aciclovir, valaciclovir and other antivirals. [1] A study has found that it is more effective than aciclovir, but this has been disputed because of a possible conflict of interest on part of the study authors.