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DNA origami object from viral DNA visualized by electron tomography. [1] The map is at the top and atomic model of the DNA colored below. (Deposited in EMDB EMD-2210) . DNA origami is the nanoscale folding of DNA to create arbitrary two- and three-dimensional shapes at the nanoscale.
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The Gibbs free energy of a perfectly matched nucleic acid duplex can be predicted using a nearest neighbor model. This model considers only the interactions between a nucleotide and its nearest neighbors on the nucleic acid strand, by summing the free energy of each of the overlapping two-nucleotide subwords of the duplex.
Among these devices are force-sensing nano-structures, [2] gigadalton-sized DNA assemblies, [3] dynamically switching devices, [4] molecular motors, [5] [6] and virus traps. [ 7 ] [ 8 ] In the long term, Dietz hopes to make a significant contribution to the creation of molecular machines and systems with practical benefits for everyday life.
Rothemund's DNA origami contains a long strand which folding is assisted by several short strands. This method allowed forming much larger structures than formerly possible, and which are less technically demanding to design and synthesize. [7] DNA origami was the cover story of Nature on March 15, 2006. [13]
Printable sheet to make a metro train of the Valencia Metro (Venezuela). This may be considered a broad category that contains origami and card modeling. Origami is the process of making a paper model by folding a single piece of paper without using glue or cutting while the variation kirigami does.
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The two pathways for homologous recombination in eukaryotes, showing the formation and resolution of Holliday junctions. The Holliday junction is a key intermediate in homologous recombination, a biological process that increases genetic diversity by shifting genes between two chromosomes, as well as site-specific recombination events involving integrases.