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After making various guest appearances on Law & Order: Special Victims Unit, Dragnet (2003), and NUMB3RS, Callies gained a starring role on Fox's Prison Break as Sara Tancredi. She played the role in the first two seasons, but her character was killed off for the third season before being brought back for the fourth season.
Sara Tancredi (played by Sarah Wayne Callies) is Michael's love interest, and later wife, daughter of the Illinois governor Frank Tancredi, and a doctor working at Fox River State Penitentiary before becoming involved in the conspiracy behind Lincoln Burrows' setup.
The General offers a $100,000 bounty for Sara's death. Sara is poisoned, but is saved by the prison doctor, who informs her that her baby will be taken away shortly after its birth. Michael asks Warden Simms to protect Sara, but she refuses. Michael decides that he must break Sara out, enlisting Lincoln Burrows and Fernando Sucre's help ...
The 46-year-old actor, who starred as Dr Sara Tancredi on the series – which ran from 2005 to 2017 – currently co-hosts the Prison Breaking rewatch podcast with former co-star Paul Adelstein ...
He explained, "Prison Break got to a point where a lot of the stories had been told." At the time, he said there was a possibility of adding two extra episodes, he said "We want to finish strong." [1] These extra two episodes became Prison Break: The Final Break, although they never aired on Fox, and became available only on DVD.
Meanwhile, Sara Tancredi, upon discovering she has lost Bruce Bennett's credit card, realizes she is being followed. She makes a run for it and manages to elude Wyatt , the Company's assassin. Agent Self, by making up a story about Al-Qaeda using stolen bearer bonds , manages to barge into the cardholder's office in the Treasury Department .
Governor Tancredi, Sara's father, arrives in the prison personally with plans on having the prison raided, which is agreed by Bellick but not by Pope. Scofield manages to rescue Sara from the violent prisoners in sickbay.
After arriving in Gila, New Mexico, Agent Mahone (William Fichtner) calls Agent Kellerman, who is on his way to Willcox, Arizona, to tell him that he is closing on Michael Scofield (Wentworth Miller) and Sara Tancredi (Sarah Wayne Callies). Mahone visits several hotels in Gila and finally finds the one Sara stayed at under the alias, Kelli Foster.