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  2. 4-Piperidone - Wikipedia

    en.wikipedia.org/wiki/4-Piperidone

    4-Piperidone is an organic compound with the molecular formula OC(CH 2) 4 NH. It can be viewed as a derivative of piperidine. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs. Substituted and dehydro derivatives of 4-piperidinone are intermediates in alkaloid syntheses. [1]

  3. Piperidine - Wikipedia

    en.wikipedia.org/wiki/Piperidine

    N-Methyl-3-piperidyl benzilate (JB-336, BZ) Piperidine is also commonly used in chemical degradation reactions, such as the sequencing of DNA in the cleavage of particular modified nucleotides. Piperidine is also commonly used as a base for the deprotection of Fmoc-amino acids used in solid-phase peptide synthesis.

  4. DEA list of chemicals - Wikipedia

    en.wikipedia.org/wiki/DEA_list_of_chemicals

    Methyl alpha-phenylacetoacetate (MAPA; methyl 3-oxo-2-phenylbutanoate) and its optical isomers phenylacetone, methamphetamine, amphetamine: 4-Piperidone: fentanyl: 1-boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) and its salts fentanyl

  5. N-Methyl-2-pyrrolidone - Wikipedia

    en.wikipedia.org/wiki/N-Methyl-2-pyrrolidone

    N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam. It is a colorless liquid, although impure samples can appear yellow. It is miscible with water and with most common organic solvents. It also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide.

  6. N-Phenethyl-4-piperidinone - Wikipedia

    en.wikipedia.org/wiki/N-Phenethyl-4-piperidinone

    Paul Janssen (founder of Janssen Pharmaceutica) first synthesized fentanyl in 1960 from Benzylfentanyl. [4] The Siegfried method (shown below and published on The Hive ) involves reacting N -phenethyl-4-piperidinone with aniline , and then reducing the imine product with sodium borohydride to 4-anilino- N -phenethylpiperidine (ANPP).

  7. 4-Pyridone - Wikipedia

    en.wikipedia.org/wiki/4-Pyridone

    4-Pyridone exists a keto-enol tautomerism with its enol tautomer 4-hydroxypyridine. In solution, the keto tautomer is favoured, [4] and the enol tautomer only becomes important in very dilute solutions or solutions of non-polar solvents. However, the enol tautomer is dominant in the gas phase. [5]

  8. Pempidine - Wikipedia

    en.wikipedia.org/wiki/Pempidine

    These are very similar in principle: Leonard and Hauck reacted phorone with ammonia, to produce 2,2,6,6-tetramethyl-4-piperidone, which was then reduced by means of the Wolff–Kishner reduction to 2,2,6,6-tetramethylpiperidine. This secondary amine was then N-methylated using methyl iodide and potassium carbonate. [6]

  9. Piperidinone - Wikipedia

    en.wikipedia.org/wiki/Piperidinone

    Piperidinones or piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine. [1]

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