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The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
Long-term effects were also a concern, as patients were often cured and could expect long survival after chemotherapy. Infertility was a major long-term side effect, and even more seriously, the risk of developing treatment-related myelodysplasia or acute leukemia was increased up to 14-fold in patients who received MOPP. [14]
[81] [82] Concerns regarding the long-term effects of benzodiazepines have been raised since 1980. [83] These concerns are still not fully answered. A review in 2006 of the literature on use of benzodiazepine and nonbenzodiazepine hypnotics concluded that more research is needed to evaluate the long-term effects of hypnotic drugs. [84]
Oncovin (vincristine), which prevents cells from duplicating by binding to the protein tubulin; Prednisone or Prednisolone, which are corticosteroids. Sometimes the chimeric anti-CD20 monoclonal antibody, rituximab, is added to this treatment regimen to form the R-CHOP regimen.
6 Potential Long-Term Effects of Ozempic. You may have heard about — or maybe even experienced — the short-term side effects of Ozempic® — such as nausea, vomiting, constipation, and diarrhea.
How long do Plan B side effects usually last? Again, it totally varies from person to person—but here’s what Dr. Jackson-Bey says you might expect: Day 1: After taking the pill, you might have ...
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Authors report resting metabolism in this area is associated with performance on short-term memory tasks. [14] While post-treatment studies suggest significant negative side effects of chemotherapy on cognition, other studies have indicated that there may be baseline vulnerability factors which could contribute to cognitive impairment development.