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Expressed mostly in neurons (where it is believed to be the main glucose transporter isoform), and in the placenta. Is a high-affinity isoform, allowing it to transport even in times of low glucose concentrations. GLUT4: Expressed in adipose tissues and striated muscle (skeletal muscle and cardiac muscle). Is the insulin-regulated glucose ...
GLUT4 has a Km value for glucose of about 5 mM, which as stated above is the normal blood glucose level in healthy individuals. GLUT4 is the most abundant glucose transporter in skeletal muscle and is thus considered to be rate limiting for glucose uptake and metabolism in resting muscles. [8]
Glucose is a monosaccharide containing six carbon atoms and an aldehyde group, and is therefore an aldohexose. The glucose molecule can exist in an open-chain (acyclic) as well as ring (cyclic) form. Glucose is naturally occurring and is found in its free state in fruits and other parts of plants.
SLC5A4, also known as SGLT3, is a member of the sodium-glucose cotransporter family. Unlike SGLT1 and SGLT2, which are efficient glucose transporters, SGLT3 functions primarily as a glucose sensor rather than a transporter. It has a low affinity for glucose and does not significantly contribute to glucose transport across cell membranes.
Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene. [ 5 ] [ 6 ] SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. [ 6 ]
170441 Ensembl ENSG00000197496 ENSMUSG00000027661 UniProt O95528 Q8VHD6 RefSeq (mRNA) NM_030777 NM_130451 RefSeq (protein) NP_110404 NP_569718 Location (UCSC) Chr 20: 46.71 – 46.74 Mb Chr 2: 165.35 – 165.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene ...
Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene. [ 5 ] [ 6 ] [ 7 ] This gene encodes a member of the SLC2A facilitative glucose transporter family.
Solute carrier family 2 (facilitated glucose transporter), member 14 is a protein that in humans is encoded by the SLC2A14 gene. [ 5 ] Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells .