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  2. ATC code C09 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_C09

    ATC code C09 Agents acting on the renin–angiotensin system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.

  3. Tetracycline-controlled transcriptional activation - Wikipedia

    en.wikipedia.org/wiki/Tetracycline-controlled...

    A Tet-On system works similarly, but in the opposite fashion. While in a Tet-Off system, tTA is capable of binding the operator only if not bound to tetracycline or one of its derivatives, such as doxycycline, in a Tet-On system, the rtTA protein is capable of binding the operator only if bound by a tetracycline. Thus the introduction of ...

  4. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below.

  5. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .

  6. Auxiliary label - Wikipedia

    en.wikipedia.org/wiki/Auxiliary_Label

    Deciding what auxiliary labels are suitable for a particular prescription requires knowledge of the drug's classification, interactions, and side effects. [10] One study of auxiliary label usage found that about 80% of dispensed prescriptions would benefit from at least one auxiliary label to reinforce information, or provide additional ...

  7. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.

  8. Amlodipine - Wikipedia

    en.wikipedia.org/wiki/Amlodipine

    Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]

  9. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...