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The evolutionary history of EFL is unclear. It may have arisen one or more times followed by loss of EFL or EF-1α. The presence in three diverse eukaryotic groups (fungi, chromalveolates, and archaeplastida) is supposed to be the result of two or more horizontal gene transfer events, according to a 2009 review. [5]
Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes.In humans, it is encoded by the EEF1A1 gene. [5] [6]This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome.
Eukaryotic translation is the biological process by which messenger RNA is translated into proteins in eukaryotes. It consists of four phases: initiation, elongation, termination, and recapping. It consists of four phases: initiation, elongation, termination, and recapping.
Note that EIF5A, the archaeal and eukaryotic homolog to EF-P, was named as an initiation factor but now considered an elongation factor as well. [ 6 ] In addition to their cytoplasmic machinery, eukaryotic mitochondria and plastids have their own translation machinery, each with their own set of bacterial-type elongation factors.
1937 67160 Ensembl ENSG00000254772 ENSMUSG00000071644 UniProt P26641 Q9D8N0 RefSeq (mRNA) NM_001404 NM_026007 RefSeq (protein) NP_001395 NP_080283 Location (UCSC) Chr 11: 62.56 – 62.57 Mb Chr 19: 8.94 – 8.96 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Elongation factor 1-gamma is a protein that in humans is encoded by the EEF1G gene. Function This gene encodes a subunit of ...
A gunman opened fire at an adult education center in the Swedish city of Örebro on Tuesday, killing at least 10 people in what the country’s prime minister called the “worst mass shooting in ...
The Bengal cat breed was created by crossing the Asian leopard cat (ALC) with domestic cats to produce a gorgeous spotted cat breed. This took place in the 1970s and their popularity has increased ...
Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help stabilize the formation of ribosomal preinitiation complexes around the start codon and are an important input for post-transcription gene regulation .