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  2. Ceftriaxone - Wikipedia

    en.wikipedia.org/wiki/Ceftriaxone

    Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]

  3. Cephalosporin - Wikipedia

    en.wikipedia.org/wiki/Cephalosporin

    Structure of the classical cephalosporins. The cephalosporins (sg. / ˌ s ɛ f ə l ə ˈ s p ɔːr ɪ n, ˌ k ɛ-,-l oʊ-/ [1] [2]) are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as Cephalosporium. [3] Together with cephamycins, they constitute a subgroup of β-lactam antibiotics ...

  4. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    The hydrolysis of the β-lactam ring by β-lactamase enzymes renders the antibiotic ineffective, thereby allowing the bacteria to survive in the presence of the antibiotic. [28] Some β-lactam antibiotics like ceftriaxone and meropenem are known to be relatively unstable in solution, especially when stored for extended periods, and degrade in ...

  5. List of β-lactam antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

    This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.

  6. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Antibiotics with less reliable but occasional (depending on isolate and subspecies) activity: occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate, and piperacillin-tazobactam (not all vancomycin-resistant Enterococcus isolates are resistant to penicillin and ampicillin)

  7. Beta-lactamase - Wikipedia

    en.wikipedia.org/wiki/Beta-lactamase

    ESBLs are beta-lactamases that hydrolyze extended-spectrum cephalosporins with an oxyimino side chain. These cephalosporins include cefotaxime, ceftriaxone, and ceftazidime, as well as the oxyimino-monobactam aztreonam. Thus ESBLs confer multi-resistance to these antibiotics and related oxyimino-beta lactams. In typical circumstances, they ...

  8. Cefixime - Wikipedia

    en.wikipedia.org/wiki/Cefixime

    Cefixime is contraindicated in patients with known sensitivity or allergies to cephalosporin class of antibiotics. [11] [16] As Cefixime is a third generation cephalosporin, it is not contraindicated for patients with a true penicillin allergy.

  9. Discovery and development of cephalosporins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The cephalosporins (and other β-lactams) have the ability to kill bacteria by inhibiting essential steps in the bacterial cell wall synthesis which in the end results in osmotic lysis and death of the bacterial cell. [2] Cephalosporins are widely used antibiotics because of their clinical efficiency and desirable safety profile. [3]