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Nicotine has been used as an insecticide since at least 1690, in the form of tobacco extracts or as pure nicotine sulphate [19] [49] [50] (although other components of tobacco also seem to have pesticide effects). [51] It acts on the nicotinic acetylcholine receptor, and gave the receptor its name. Nicotine is in IRAC group 4B.
A nicotine base and a weak acid such as benzoic acid or levulinic acid is used to form a nicotine salt. [1] Across a sample of 23 nicotine salts available for public purchase, the three most common acids used in the formation of nicotine salts were lactic acid, benzoic acid and levulinic acid. [8]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
Everclear is an American brand name of a line of rectified spirit (also known as grain alcohol and neutral spirit) produced by the American company Luxco (formerly known as the David Sherman Corporation, and since 2021 a subsidiary of MGP Ingredients).
Zyn pouches are sold in round cans containing 15 or 20 pouches depending on the market. Pouches are available in different levels of nicotine strength (such as 3 or 6 milligrams per pouch in the US) and different flavored and unflavored varieties. [17] The pouches contain nicotine extracted from tobacco leaves, and food grade ingredients. [18]
Nicotiana rustica, commonly known as Aztec tobacco [2] or strong tobacco, [3] is a rainforest plant in the family Solanaceae native to South America.It is a very potent variety of tobacco, containing up to nine times more nicotine than common species of Nicotiana such as Nicotiana tabacum (common tobacco). [4]