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Apolipoprotein B is the primary apolipoprotein of chylomicrons, VLDL, Lp(a), IDL, and LDL particles (LDL—commonly known as "bad cholesterol" when in reference to both heart disease and vascular disease in general), which is responsible for carrying fat molecules (), including cholesterol, around the body to all cells within all tissues.
In a 2021 study in the journal The Lancet, researchers found that elevated levels of Apo B were associated with shorter lifespans, and the data suggested it was a stronger predictor than LDL levels.
The patient can have hypobetalipoproteinemia and simultaneously have high levels of HDL cholesterol. Notably, in people who do not have the genetic disorder hypobetalipoproteinemia, a very low cholesterol level (less than 100 mg/dl) may be a marker for poor nutrition, wasting disease, cancer, hyperthyroidism, and liver disease.
Apolipoprotein B deficiency is an autosomal dominant disorder resulting from a missense mutation which reduces the affinity of apoB-100 for the low-density lipoprotein receptor (LDL Receptor). This causes impairments in LDL catabolism, resulting in increased levels of low-density lipoprotein in the blood.
The book has been translated and adapted by women's groups around the world and is available in 33 languages. [3] Sales for all the books exceed four million copies. [4] The New York Times has called the seminal book "America's best-selling book on all aspects of women's health" and a "feminist classic". [5]
Most women over 60 have entered a new phase in life and health: post-menopause. According to Dr. Tara Scott, MD, gynecologist and Medical Advisor at Versalie, by the age of 60, most women are ...
Welcome to Better Sex With Dr. Lexx, a monthly column where sex therapist, educator and consultant Dr. Lexx Brown-James shares expertise, advice and wisdom about sex, relationships and more.
[1] [10] What people eat can also have an influence, with excessive alcohol use, too much carbohydrates, and diets high in saturated fats having a higher risk. [1] Some medications that may contribute to dyslipidemia are thiazide diuretics , beta blockers , oral contraceptives , atypical antipsychotics (clozapine, olanzapine), corticosteroids ...