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XY complete gonadal dysgenesis, also known as Swyer syndrome, is a type of defect hypogonadism in a person whose karyotype is 46,XY. Though they typically have normal vulvas , [ 1 ] the person has underdeveloped gonads, fibrous tissue termed " streak gonads ", and if left untreated, will not experience puberty .
[1] [2] One type of gonadal dysgenesis is the development of functionless, fibrous tissue, termed streak gonads, instead of reproductive tissue. [3] Streak gonads are a form of aplasia , resulting in hormonal failure that manifests as sexual infantism and infertility , with no initiation of puberty and secondary sex characteristics .
[144] [145] Looking east down Thousand Oaks Boulevard Los Robles Hospital has earned multiple top honors for its specialized care. [146] [147] SAGE Publishing is headquartered in Newbury Park, CA. While agriculture was the dominant industry in Thousand Oaks until the 1950s, a number of high-tech companies moved to Newbury Park in the 1960s.
Pseudohermaphroditism is an outdated [1] term for when an individual's gonads were mismatched with their internal reproductive system and/or external genitalia. The term was contrasted with " true hermaphroditism " (now known as ovotesticular syndrome ), a condition describing an individual with both female and male reproductive gonadal tissues.
Meanwhile, XY gonadal dysgenesis is known as PGD, 46,XY or Swyer syndrome. Patients with PGD have a normal chromosomal constellation but may have localized genetic alterations. XX gonadal dysgenesis is related to Swyer syndrome, since both conditions have the same phenotype and clinical issues; however in Swyer syndrome the karyotype is 46,XY ...
Leading to the presence of 2 vaginas, 2 uteruses, a single kidney. Can also affect the spleen, bladder and other urogenital structures. [40] [41] Isolated 17,20-lyase deficiency – a condition that is characterized by either partial or complete inability to produce androgens and estrogens. [42]
The development of both is controlled by sex hormones produced by the body after the initial fetal stage where the presence or absence of the Y-chromosome and/or the SRY gene determine development. Male primary sex characteristics are the penis, the scrotum and the ability to ejaculate when matured.
Dos Vientos is a neighborhood of Thousand Oaks, California in westernmost portion of Newbury Park. Bordering Dos Vientos Open Space and the Santa Monica Mountains, it was a 2,350-unit housing development which was approved by the Thousand Oaks City Council in April 1988. [1] It is an upscale [2] and master-planned [3] community.