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Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [ 9 ] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10 ] the term was adopted by the American ...
Multiple lines of evidence on the mechanisms and phenomenology of depression suggest that mild to moderate (or "normative") depressed states preserve an individual's inclusion in key social contexts via three intersecting features: a cognitive sensitivity to social risks and situations (e.g., "depressive realism"); it inhibits confident and ...
t. e. Dialectical behavior therapy (DBT) is an evidence-based [1] psychotherapy that began with efforts to treat personality disorders and interpersonal conflicts. [1] Evidence suggests that DBT can be useful in treating mood disorders and suicidal ideation as well as for changing behavioral patterns such as self-harm and substance use. [2]
MeSH. D015928. [edit on Wikidata] Cognitive behavioral therapy (CBT) is a form of psychotherapy [1][2] that aims to reduce symptoms of various mental health conditions, primarily depression, PTSD and anxiety disorders. [3] Cognitive behavioral therapy focuses on challenging and changing cognitive distortions (such as thoughts, beliefs, and ...
e. Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people of all ages (as of 2020). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]
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