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This number is known as the Corsi Span, and average is about 5–6 for normal human subjects. An fMRI study involving subjects undergoing this test revealed that while the sequence length increases, general brain activity remains the same. So while humans may show encoding difficulty, this is not related to overall brain activation.
In one study, researchers found significantly differing activity between healthy and schizophrenic patients in the left dorsal parietal cortex and left ventrolateral prefrontal cortex; as these regions are essential components of a frontal-parietal executive system, hypo-activity in these regions for schizophrenia patients during working memory ...
Functional magnetic resonance imaging (fMRI) has intriguing implications for the study of memory in humans, however it can also be used in animal models. fMRI can be used to assess brain functionality in monkeys in the context of a variety of behavioral tasks. [26]
[87] and fMRI [88] The latter study further demonstrated that working memory in the AVS is for the acoustic properties of spoken words and that it is independent to working memory in the ADS, which mediates inner speech. Working memory studies in monkeys also suggest that in monkeys, in contrast to humans, the AVS is the dominant working memory ...
In the working memory task, heavy lifetime cannabis use was associated with lower brain activation, a link that remained even when discounting participants who had recently used cannabis.
Another study by the same group [81] has shown that, after training, measured brain activity related to working memory increased in the prefrontal cortex, an area that many researchers have associated with working memory functions. One study has shown that working memory training increases the density of prefrontal and parietal dopamine ...
More frequent use of cannabis may impair working memory, which could lead to problems with everyday tasks, a new study suggests. “Working memory involves the ability to keep a small amount of ...
In fMRS, depending on the focus of the study, either single-voxel or multi-voxel spectroscopic technique can be used. In single-voxel fMRS the selection of the volume of interest (VOI) is often done by running a functional magnetic resonance imaging (fMRI) study prior to fMRS to localize the brain region activated by the task. Single-voxel ...