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Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications. Common sites for intramuscular injections include the deltoid muscle of the upper arm and the gluteal muscle of the buttock. In infants, the vastus lateralis muscle of the thigh is commonly used. The injection ...
The vaccine delivery method/route may vary. They may be given by injection, dermal application, or nasal/ocular application. Injection routes may be intra-muscular (IM) or subcutaneous (SQ). The specific injection site may vary depending on the type of vaccine (MLV vs killed) being given.
Side effects in animals include nephrotoxicity, ototoxicity, and allergic reactions at IM injection sites. Cats tend to be more sensitive to the vestibular damage caused by ototoxicity. Less frequent side effects include neuromuscular blockade, facial edema, and peripheral neuropathy. [8] [35] The half-life in most animals is one to two hours. [43]
Intramuscular injection is the administration of a drug deep into the muscles via a needle, which allows the drug to go into the bloodstream as well. Subcutaneous injections occur when the needle is inserted between the skin and muscle, allowing the drug to be absorbed into the bloodstream over a prolonged period. [ 27 ]
Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
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The term injection encompasses intravenous (IV), intramuscular (IM), subcutaneous (SC) and intradermal (ID) administration. [35] Parenteral administration generally acts more rapidly than topical or enteral administration, with onset of action often occurring in 15–30 seconds for IV, 10–20 minutes for IM and 15–30 minutes for SC. [36]
Image credits: caspii2 First created exactly 13 years ago on February 5, 2012, ‘Mildly Interesting’ has grown to become a second home to a whopping 24 million members from all corners of the ...