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Mitochondrial uncoupling protein 3 (UCP3) is a members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and transfer of protons from the outer to the inner mitochondrial membrane, reducing the mitochondrial membrane potential in mammalian cells.
For example, 3 is a Mersenne prime as it is a prime number and is expressible as 2 2 − 1. [1] [2] The exponents p corresponding to Mersenne primes must themselves be prime, although the vast majority of primes p do not lead to Mersenne primes—for example, 2 11 − 1 = 2047 = 23 × 89. [3]
Structure of the human uncoupling protein UCP1. An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter.An uncoupling protein is thus capable of dissipating the proton gradient generated by NADH-powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space.
In contrast to UCP1 and UCP3, which are primarily expressed in adipose and smooth muscle, UCP2 is expressed on many different tissues [6] including the kidney, liver, GI tract, brain, and skeletal muscle. The exact mechanisms of anion transfer by UCPs are not known. [7] UCPs contain the three homologous protein domains of MACPs.
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The books in this series, like the other Springer-Verlag mathematics series, are small yellow books of a standard size. The books in this series tend to be written at a more elementary level than the similar Graduate Texts in Mathematics series, although there is a fair amount of overlap between the two series in terms of material covered and ...
Despite being marketed as a supplement, several titles have become widely used as primary textbooks for courses [citation needed] (the Discrete Mathematics and Statistics titles are examples). This is particularly true in settings where an important factor in the selection of a text is the price, such as in community colleges.
22227 Ensembl ENSG00000109424 ENSMUSG00000031710 UniProt P25874 P12242 RefSeq (mRNA) NM_021833 NM_009463 RefSeq (protein) NP_068605 NP_033489 Location (UCSC) Chr 4: 140.56 – 140.57 Mb Chr 8: 84.02 – 84.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is a mitochondrial ...