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  2. Methylsulfonylmethane - Wikipedia

    en.wikipedia.org/wiki/Methylsulfonylmethane

    Methylsulfonylmethane is marketed as a dietary supplement with medical claims ranging from anti-inflammatory effects for pain management, skin condition and aging treatments, and immune system modulation. [9] [10] [11] No medical uses for MSM have been approved and there is limited evidence to support most of the claims.

  3. Liniment - Wikipedia

    en.wikipedia.org/wiki/Liniment

    The equine version of Absorbine is sometimes used by humans, [22] though, anecdotally, its benefits in humans may be because the smell of menthol releases serotonin, or due to a placebo effect. [20] Earl Sloan was a US entrepreneur who made his initial fortune selling his father's horse liniment formula beginning in the period following the ...

  4. Animal disease model - Wikipedia

    en.wikipedia.org/wiki/Animal_disease_model

    Humans share about 99% of our genome with chimpanzees [7] [8] (98.7% with bonobos) [9] and over 90% with the mouse. [6] With so much of the genome conserved across species, it is relatively impressive that the differences between humans and mice can be accounted for in approximately six thousand genes (of ~30,000 total).

  5. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    No data were available for doxylamine in terms of longer-term treatment (3 months). [14] For comparison, the other sedating medicines assessed, doxepin and trimipramine (both of which are tricyclic antidepressants) had effect sizes (SMD) at 4 weeks of 0.30 (95% CI –0.05 to 0.64) (very low certainty evidence) and 0.55 (95% CI –0.11 to 1.21 ...

  6. Management of tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_tuberculosis

    The main result was a relative risk (RR) of 0.40 (95% confidence interval (CI) 0.31 to 0.52) for development of active tuberculosis over two years or longer for patients treated with INH, with no significant difference between treatment courses of six or 12 months (RR 0.44, 95% CI 0.27 to 0.73 for six months, and 0.38, 95% CI 0.28 to 0.50 for ...

  7. Placebo-controlled study - Wikipedia

    en.wikipedia.org/wiki/Placebo-controlled_study

    The efficacy of the active drug's active ingredient: the difference between A and P (i.e., A-P). The magnitude of the placebo response: the difference between P and NH (i.e., P-NH). It is a matter of interpretation whether the value of P-NH indicates the efficacy of the entire treatment process or the magnitude of the "placebo response". The ...