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Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox , and shingles . [ 6 ] Other uses include, prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection.
Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza: Influenza A virus M2 proton channel antagonist 1966 Ampligen: Avian Influenza: Immunomodulatory double-stranded RNA: 2016 Amprenavir (Agenerase) HIV
One antiviral strategy is to interfere with the ability of a virus to infiltrate a target cell. The virus must go through a sequence of steps to do this, beginning with binding to a specific "receptor" molecule on the surface of the host cell and ending with the virus "uncoating" inside the cell and releasing its contents. Viruses that have a ...
Antiviral Medications: Antiviral drugs such as acyclovir may be prescribed for viral folliculitis. Topical Antibiotics : Prescription-strength antibiotics like clindamycin or erythromycin.
Treatment: There are several antiviral medications to treat shingles, including acyclovir, valacyclovir, and famciclovir, per the CDC. Cool compresses, oatmeal baths, and calamine lotion may also ...
It is comparable in effectiveness to prescription topical antiviral agents. Due to docosanol's mechanism of action, there is little risk of drug resistance. [40] Antivirals creams include acyclovir and penciclovir, which can speed healing by as much as 10%. [41] [1] Oral antivirals include acyclovir, valaciclovir, and famciclovir. [1]
Schedule H is a class of prescription drugs in India appearing as an appendix to the Drugs and Cosmetics Rules, 1945 introduced in 1945. These are drugs which cannot be purchased over the counter without the prescription of a qualified doctor. The manufacture and sales of all drugs are covered under the Drugs and Cosmetics Act and Rules.
Mutations occur in the enzymes that phosphorylate the drug and activate it: in the case of herpes simplex, resistance to acyclovir arises due to a mutation affecting the viral enzyme thymidine kinase. Since nucleoside analogues require two phosphorylations to be activated, one carried out by a viral enzyme and the other by enzymes in the host ...