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  2. Titration curve - Wikipedia

    en.wikipedia.org/wiki/Titration_curve

    A typical titration curve of a diprotic acid, oxalic acid, titrated with a strong base, sodium hydroxide.Both equivalence points are visible. Titrations are often recorded on graphs called titration curves, which generally contain the volume of the titrant as the independent variable and the pH of the solution as the dependent variable (because it changes depending on the composition of the ...

  3. Equivalence point - Wikipedia

    en.wikipedia.org/wiki/Equivalence_point

    The equivalence point, or stoichiometric point, of a chemical reaction is the point at which chemically equivalent quantities of reactants have been mixed. For an acid-base reaction the equivalence point is where the moles of acid and the moles of base would neutralize each other according to the chemical reaction.

  4. Acid–base titration - Wikipedia

    en.wikipedia.org/wiki/Acid–base_titration

    pH after the equivalence point; 1. The initial pH is approximated for a weak acid solution in water using the equation: [1] = ⁡ [+] where [+] is the initial concentration of the hydronium ion. 2. The pH before the equivalence point depends on the amount of weak acid remaining and the amount of conjugate base formed.

  5. Titration - Wikipedia

    en.wikipedia.org/wiki/Titration

    The equivalence point occurs between pH 8-10, indicating the solution is basic at the equivalence point and an indicator such as phenolphthalein would be appropriate. Titration curves corresponding to weak bases and strong acids are similarly behaved, with the solution being acidic at the equivalence point and indicators such as methyl orange ...

  6. Neutralization (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Neutralization_(chemistry)

    The pH at the end-point or equivalence point in a titration may be calculated as follows. At the end-point the acid is completely neutralized so the analytical hydrogen ion concentration, T H, is zero and the concentration of the conjugate base, A −, is equal to the analytical or formal concentration T A of the acid: [A −] = T A.

  7. Gran plot - Wikipedia

    en.wikipedia.org/wiki/Gran_plot

    For a strong acid-strong base titration monitored by pH, we have at any i'th point in the titration = [+] [] where K w is the water autoprotolysis constant.. If titrating an acid of initial volume and concentration [+] with base of concentration [], then at any i'th point in the titration with titrant volume ,

  8. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    From the titration of protonatable group, one can read the so-called pK a 1 ⁄ 2 which is equal to the pH value where the group is half-protonated (i.e. when 50% such groups would be protonated). The pK a 1 ⁄ 2 is equal to the Henderson–Hasselbalch pK a (pK HH a) if the titration curve follows the Henderson–Hasselbalch equation. [14]

  9. Salt bridge (protein and supramolecular) - Wikipedia

    en.wikipedia.org/wiki/Salt_bridge_(protein_and...

    A titration is performed, while recording the chemical shift corresponding to the protons of the carbon adjacent to the carboxylate or ammonium group. The midpoint of the titration curve corresponds to the pK a, or the pH where the ratio of protonated: deprotonated molecules is 1:1. Continuing with the T4 lysozyme example, a titration curve is ...