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  2. Anti-SSA/Ro autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-SSA/Ro_autoantibodies

    Immunofluorescence pattern of SS-A and SS-B antibodies. Produced using serum from a patient on HEp-20-10 cells with a FITC conjugate. Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA, anti–SS-A/Ro, and anti-Ro/SS-A) are a type of anti-nuclear autoantibodies that are associated with ...

  3. Extractable nuclear antigen - Wikipedia

    en.wikipedia.org/wiki/Extractable_nuclear_antigen

    anti-Ro/anti-SS-A(for Sjögren's) anti-Scl70 (for Scleroderma) anti-Jo (for Dermatomyositis) Sensitivity and specificity of these tests depends on the type of assay employed, and will therefore vary by lab. The following table illustrates the sensitivity and specificity of ENA antibodies at detecting SLE with the ELISA technique.

  4. Antinuclear antibody - Wikipedia

    en.wikipedia.org/wiki/Antinuclear_antibody

    This staining pattern is seen with anti-Ro and anti-La antibodies. Anti-Ro and anti-La antibodies, also known as SS-A and SS-B, respectively, are commonly found in primary Sjögren's syndrome, an autoimmune disorder that affects the exocrine glands. The presence of both antibodies is found in 30–60% of Sjögren's syndrome, anti-Ro antibodies ...

  5. Neonatal lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Neonatal_lupus_erythematosus

    Neonatal lupus erythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies. [1] [2] The disease most commonly presents with a diffuse/periorbital rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly. [3]

  6. List of autoimmune diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_autoimmune_diseases

    21-hydroxylase antibodies Confirmed 0.93-1.4 per 10,000 [72] Autoimmune oophoritis: Ovaries: Anti-ovarian antibodies Probable Rare [73] Autoimmune orchitis: Testes: Anti-sperm antibodies Probable Rare [74] Autoimmune pancreatitis: Pancreas: IgG4, Anti-CA2 antibodies Confirmed 0.82-1.3 per 100,000 [75] Autoimmune polyendocrine syndrome type 1 (APS1)

  7. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    Antibody profiling is used for identifying persons from forensic samples. The technology can uniquely identify a person by analyzing the antibodies in body fluids. A unique, individual set of antibodies, called individual specific autoantibodies (ISA), is found in blood, serum, saliva, urine, semen, perspiration, tears, and body tissues, and ...

  8. Antisynthetase syndrome - Wikipedia

    en.wikipedia.org/wiki/Antisynthetase_syndrome

    Autoantibodies often tested include anti-Ro/SSA, [38] anti-nuclear antibody, anti-U1-RNP, anti-Ku, and anti-PM-Scl. [37] Although anti-La/SSB and anti-Ro/SSA are often associated with Sjogren's syndrome they have been associated with antisynthetase syndrome and severe fibrotic idiopathic interstitial lung disease by high-resolution computed ...

  9. Anti-histone antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-histone_antibodies

    Anti-histone antibodies are autoantibodies that are a subset of the anti-nuclear antibody family, which specifically target histone protein subunits or histone complexes. [1] They were first reported by Henry Kunkel , H.R. Holman, and H.R.G. Dreicher in their studies of cellular causes of lupus erythematosus in 1959–60.