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D. latum causes B12 deficiency in humans [10] leading to megaloblastic or pernicious anemia. [ 11 ] [ 12 ] The worm absorbs around 80% of dietary B12 and prolonged infection can also cause abdominal pain, mechanical obstruction, and symptoms of iron deficiency anemia. [ 13 ]
Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of vitamin B 12 . A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia .
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
If you’re unsure whether your cat needs a medical evaluation, try calling the ASPCA Animal Poison Control Center (888-426-4435) or the Pet Poison Hotline (855-764-7661).
A minimal presence of cobalt in soils therefore markedly improves the health of grazing animals, and an uptake of 0.20 mg/kg a day is recommended because they have no other source of vitamin B 12. [3] Proteins based on cobalamin use corrin to hold the cobalt. Coenzyme B 12 features a reactive C-Co bond that participates in the reactions. [4]
Cyanide poisoning inhibits aerobic respiration and therefore increases anaerobic glycolysis which causes a rise of lactate in the plasma. A lactate concentration above 10 mmol per liter is an indicator of cyanide poisoning, as defined by the presence of a blood cyanide concentration above 40 μmol per liter.
Vitamin B 12 deficiency is but one among the conditions that can lead to dysfunction of this enzyme and a buildup of its substrate, methylmalonic acid, the elevated level of which can be detected in the urine and blood. Due to the lack of available radioactive Vitamin B 12, the Schilling test is now largely a historical artifact.
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