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The specialized olfactory receptor neurons of the olfactory nerve are located in the olfactory mucosa of the upper parts of the nasal cavity.The olfactory nerves consist of a collection of many sensory nerve fibers that extend from the olfactory epithelium to the olfactory bulb, passing through the many openings of the cribriform plate, a sieve-like structure of the ethmoid bone.
Each glomerulus is composed of two compartments, the olfactory nerve zone and the non-olfactory nerve zone. The olfactory nerve zone is composed of preterminals and terminals of the olfactory nerve and is where the olfactory receptor cells make synapses on their targets. [2] The non-olfactory nerve zone is composed of the dendritic processes of ...
The main olfactory sense is derived from the more ancient neural system, broadly present across insects and mammals. [23] This system is specialized to detect volatile, airborne molecules. The accessory olfactory system is the more recently evolved structure, first appearing in the common ancestor of modern amniotes and amphibians.
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The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory neurons, and nerve fibers of the olfactory ...
The cell bodies of the ORNs are distributed among all three of the stratified layers of the olfactory epithelium. [4] Many tiny hair-like non-motile cilia protrude from the olfactory receptor cell's dendrites. The dendrites extend to the olfactory epithelial surface and each ends in a dendritic knob from which around 20 to 35 cilia protrude.
Olfactory neurons utilize a feedback system from the levels of Ca 2+ ions to activate its adaptation to prolonged smells. Due to the fact that the olfactory signal transduction uses a second messenger transduction system, the mechanism of adaptation includes several factors that mostly include CaMK or calmodulin bound to Ca 2+ ions.
Unique to the olfactory and gustatory systems, at least in mammals, is the implementation of both peripheral and central mechanisms of action. [ clarification needed ] The peripheral mechanisms involve olfactory receptor neurons which transduce a chemical signal along the olfactory nerve , which terminates in the olfactory bulb .