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Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised , especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS).
Oral hairy leukoplakia is a corrugated ("hairy") white lesion on the sides of the tongue caused by opportunistic infection with Epstein-Barr virus on a systemic background of immunodeficiency, almost always human immunodeficiency virus (HIV) infection. [15]
Oral hairy leukoplakia (seen in people with immunosuppression, caused by Epstein–Barr virus) Oral candidiasis can affect the tongue. Risk factors for oral candidiasis include antibiotic and corticosteroid use, and immunodeficiency (e.g. HIV), [5] or diabetes mellitus).
Oral manifestations of systematic disease are signs and symptoms of disease occurring elsewhere in the body detected in the oral cavity and oral secretions. High blood sugar can be detected by sampling saliva. [1] Saliva sampling may be a non-invasive way to detect changes in the gut microbiome and changes in systemic disease.
Hairy leukoplakia (oral hairy leukoplakia) Intraoral dental sinus; Linea alba; Leukoplakia; Leukoplakia with tylosis and esophageal carcinoma; Major aphthous ulcer (periadenitis mucosa necrotica recurrens) Median rhomboid glossitis (central papillary atrophy) Melanocytic oral lesion; Melkersson–Rosenthal syndrome
Hairy tongue may be confused with hairy leukoplakia, however the latter usually occurs on the sides of the tongue and is associated with an opportunistic infection with Epstein–Barr virus on a background immunocompromise (almost always human immunodeficiency virus infection but rarely other conditions which suppress the immune system).
Oral hairy leukoplakia; Pulmonary tuberculosis (TB) diagnosed in last two years; Severe presumed bacterial infections (e.g. pneumonia, empyema, meningitis, bacteraemia, pyomyositis, bone or joint infection) Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis; Conditions where confirmatory diagnostic testing is necessary ...
Diagnosis is mainly clinical, based on the history and clinical appearance. The differential diagnosis includes other oral white lesions such as Leukoplakia, squamous cell carcinoma, oral candidiasis, lichen planus, white sponge nevus and contact stomatitis. [7] In contrast to pseudomembraneous candidiasis, this white patch cannot be wiped off. [7]