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One expert says the sleep aid is "overused" by some families.
Melatonin overdoses in kids are on the rise. A top sleep expert on inaccurate labels and what parents should do before using these supplements with their kids.
From 2012 to 2021, there was a more than fivefold increase in calls to poison control centers concerning young children, most under 5, who had taken melatonin. Researchers also say the use of ...
[43] [44] Prolonged-release melatonin is safe with long-term use of up to 12 months. [11] Although not recommended for long-term use beyond this, [45] low-dose melatonin is generally safer, and a better alternative, than many prescription and over-the-counter sleep aids if a sleeping medication must be used for an extended period of time.
Melatonin use among American adults quintupled from 0.4% from 1999 to 2000 to 2.1% from 2017 to 2018, as did calls to poison control centers for pediatric melatonin exposures from 2012 to 2021 ...
[1] 6-Hydroxymelatonin is produced as a result of the enzymatic conversion of melatonin through hydroxylation. [2] Similar to melatonin, 6-OHM is a full agonist of the MT 1 and MT 2 receptors. [3] [4] It is also an antioxidant and neuroprotective, and is even more potent in this regard relative to melatonin. [5] [6]