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  2. Mallory body - Wikipedia

    en.wikipedia.org/wiki/Mallory_body

    Micrograph showing a Mallory body with the characteristic twisted-rope appearance (centre of image - within a ballooning hepatocyte). H&E stain. In histopathology, a Mallory body, Mallory–Denk body (MDB), or Mallory's hyaline is an inclusion found in the cytoplasm of liver cells. [1] Mallory bodies are damaged intermediate filaments within ...

  3. Alcoholic hepatitis - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_hepatitis

    Damaged hepatocytes release Danger associated molecular patterns (DAMPs) which are molecules that lead to further activation of the immune system's inflammatory response and further hepatocyte damage. [7] The chronic inflammation seen in alcoholic hepatitis leads to a distinctive fibrotic response, with fibrogenic cell type activation.

  4. Alcoholic liver disease - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_liver_disease

    Mallory bodies, which are also present in other liver diseases, are condensations of cytokeratin components in the hepatocyte cytoplasm and do not contribute to liver injury. Up to 70% of patients with moderate to severe alcoholic hepatitis already have cirrhosis identifiable on biopsy examination at the time of diagnosis. [13]

  5. Ballooning degeneration - Wikipedia

    en.wikipedia.org/wiki/Ballooning_degeneration

    Histopathology of a ballooning hepatocyte.png, H&E stain. Ballooning degeneration centre-left and centre-right. H&E stain. A Councilman body can also be seen in the upper-right of the section. In histo pathology, ballooning degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death.

  6. Liver cytology - Wikipedia

    en.wikipedia.org/wiki/Liver_cytology

    In the adult liver, most of the cells are binucleated, and most of the hepatocytes are tetraploid, which means that they have four times the amount of normal DNA. Their average lifespan is from approximately five months, and hepatocytes have a significant regeneration capacity after parenchymal loss by toxic processes, diseases or surgeries.

  7. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    NAFLD was defined by the presence of excess fat in the liver that cannot be explained by another factor, such as excessive alcohol use (>21 standard drinks/week for men and >14 for women in the USA; >30 g daily for men and >20 g for women in UK and EU, >140 g/week for men and >70 g/week for women in Asia-Pacific), liver injury caused by drugs ...

  8. It Took Authorities 8 Days To Find Mallory Beach After ... - AOL

    www.aol.com/took-authorities-8-days-mallory...

    Mallory Beach was killed in a boating incident involving Paul Murdaugh in 2019. Here's what to know about her death, and whether her body was ever found. It Took Authorities 8 Days To Find Mallory ...

  9. Hepatocyte - Wikipedia

    en.wikipedia.org/wiki/Hepatocyte

    Hepatocyte nuclei are round with dispersed chromatin and prominent nucleoli. Anisokaryosis (or variation in the size of the nuclei) is common and often reflects tetraploidy and other degrees of polyploidy, a normal feature of 30-40% of hepatocytes in the adult human liver. [4] Binucleate cells are also common. [citation needed]

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