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The causes of diverticulitis are unclear. [1] Risk factors may include obesity, lack of exercise, smoking, a family history of the disease, and use of nonsteroidal anti-inflammatory drugs (NSAIDs). [1] [2] The role of a low fiber diet as a risk factor is unclear. [2] Having pouches in the large intestine that are not inflamed is known as ...
Diverticulitis is defined as diverticular disease with signs and symptoms of diverticular inflammation. Clinical features of acute diverticulitis include constant abdominal pain, localized abdominal tenderness in the left lower quadrant of the abdomen, nausea, vomiting, constipation or diarrhea, fever and leukocytosis .
The cause is currently unknown. It is thought to be multi-factorial, including colonic ischemia secondary to old age and other cardiovascular risk factors, diverticulosis causing mucosal prolapse, fecal stasis and subsequent microbiome disturbance, eventually leading to inflammation of the colon segment. [7]
Perforated diverticulitis often requires surgery due to risks of infection or recurrence. Recurrent diverticulitis may required resection even in the absence of perforation. Bowel resection or repair is typically initiated earlier in patients with signs of infection, the elderly, immunocompromised, and those with severe comorbidities.
Risk factors for developing liver abscess can be due to infection, post-procedural infection and metastasis such as primary liver tumours, liver metastasis, biliary procedures, biliary injuries, biliary tract disease, appendicitis, and diverticulitis. [3] Major bacterial causes of liver abscess include the following: [4]
Risk factors include a birth defect known as intestinal malrotation, an enlarged colon, Hirschsprung disease, pregnancy, and abdominal adhesions. [1] Long term constipation and a high fiber diet may also increase the risk. [3] The most commonly affected part of the intestines in adults is the sigmoid colon with the cecum being second most ...
Risk factors for the development of bacterial overgrowth include dysmotility; anatomical disturbances in the bowel, including fistulae, diverticula and blind loops created after surgery, and resection of the ileo-cecal valve; gastroenteritis-induced alterations to the small intestine; and the use of certain medications, including proton pump ...
Several factors may influence the development of the disease, such as local colonic ischemia, fecal stasis, or mucosal prolapse. SCAD shares some features with inflammatory bowel disease, including the increase of tumor necrosis factor (TNF) alpha during active disease, and decrease in TNF during health improvement. The pathogenesis of SCAD ...