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If the systolic blood pressure is elevated (>140) with a normal (<90) diastolic blood pressure (DBP), it is called isolated systolic hypertension. [2] Eighty percent of people with systolic hypertension are over the age of 65 years old. [3] Isolated systolic hypertension is a specific type of widened (or high) pulse pressure.
Typically both systolic and diastolic pressures tend to climb or fall together, but that’s not always the case. Sometimes you can have systolic or diastolic hypertension, where one number is normal, and the other is really high, and in that situation it’s called isolated systolic hypertension or isolated diastolic hypertension.
If systolic blood pressure is elevated (>140 mmHg) with a normal diastolic blood pressure (<90 mmHg), it is called isolated systolic hypertension and may present a health concern. [ 49 ] [ 56 ] According to the 2017 [ 57 ] American Heart Association blood pressure guidelines state that a systolic blood pressure of 130–139 mmHg with a ...
This can mean that systolic pressure is abnormally high, but diastolic pressure may be normal or low, a condition termed isolated systolic hypertension. [80] The high pulse pressure in elderly people with hypertension or isolated systolic hypertension is explained by increased arterial stiffness , which typically accompanies aging and may be ...
Hypertension can also be age-related when associated with a western diet and lifestyle, and if this is the case, it is likely to be multifactorial. [23] One possible mechanism involves a reduction in vascular compliance due to the stiffening of the arteries. This can build up due to isolated systolic hypertension with a widened pulse pressure.
Efficacy and safety of levamlodipine (2.5 mg, once daily) has been evaluated in the patients with isolated systolic hypertension (ISH). Levamlodipine effectively reduced the systolic BP (mean reduction 22±14 mm of Hg) in all grades of ISH. After 28 days of the treatment, overall responder rate was 73%.