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Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief. [1] The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating. The combination is available in a number of products from various brands under different names.
More specifically, many Midol products contain a mild diuretic in their active ingredients to help with bloating. [20] Pamabrom helps relief premenstrual and menstrual symptoms of water retention. It is a xanthine derivative that acts as a mild, short-acting diuretic that eliminates sodium and chloride and sometimes potassium. [ 20 ]
It is the main active ingredient in pamabrom where it is sold as an over-the-counter medication in combination with paracetamol, among other analgesics, to treat dysmenorrhea. [ 1 ] [ 2 ] It is also an adenosine receptor A 1 antagonist .
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Box of Midol, 2023 Midol advertisement, 1960. Midol is a brand of over-the-counter analgesic drugs marketed for menstrual cramping and other effects related to premenstrual syndrome and menstruation.