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Tamsulosin is a selective α 1 receptor antagonist that has preferential selectivity for the α 1A receptor in the prostate versus the α 1B receptor in the blood vessels. [ 25 ] When alpha 1 receptors in the bladder neck, prostate, ureter, and urethra are blocked, a relaxation in smooth muscle tissue results. [ 16 ]
It is a combination of two previously existing medications: dutasteride, brand name Avodart, and tamsulosin, brand name Flomax. It contains 0.5 mg of dutasteride and 0.4 mg of tamsulosin hydrochloride. [2] Jalyn was the result of the CombAT (Combination of Avodart and Tamsulosin) trial of 2008.
Dutasteride, sold under the brand name Avodart among others, is a medication primarily used to treat the symptoms of a benign prostatic hyperplasia (BPH), an enlarged prostate not associated with cancer.
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Tamsulosin. Erythromycin. Doxazosin. You should also tell your healthcare provider if you have renal or kidney disease, angina, Peyronie’s disease, an enlarged prostate or pulmonary hypertension ...
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