Search results
Results From The WOW.Com Content Network
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
The word "titration" descends from the French word titrer (1543), meaning the proportion of gold or silver in coins or in works of gold or silver; i.e., a measure of fineness or purity. Tiltre became titre, [4] which thus came to mean the "fineness of alloyed gold", [5] and then the "concentration of a substance in a given sample". [6]
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [1] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life.
Quality control laboratories utilize acid-base titration to assess the purity of raw materials and to monitor various stages of drug manufacturing processes. [ 21 ] The technique's reliability and simplicity make it an integral tool in pharmaceutical research and development, contributing to the production of safe and effective medications.
“Additionally, with stimulant use there is a need for regular mental health evaluations and more frequent follow-ups, especially during the initiation and titration phases of amphetamine therapy.
The term also has two other, conflicting meanings. In titration, the titer is the ratio of actual to nominal concentration of a titrant, e.g. a titer of 0.5 would require 1/0.5 = 2 times more titrant than nominal. This is to compensate for possible degradation of the titrant solution.
Compounded drugs are helpful for people with allergies to certain ingredients. They also help fill a gap in supply during drug shortages (like the one currently affecting many weight loss drugs ...
Those attitudes dissipated as addicts and doctors saw that using buprenorphine did not simply mean replacing one drug with another — it worked. “Buprenorphine became the first-line treatment,” Auriacombe said, adding that the medication has helped to change public and law enforcement perceptions about addicts.