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Ultrasound is applied using a transducer or applicator that is in direct contact with the patient's skin. Gel is used on all surfaces of the head to reduce friction and assist transmission of the ultrasonic waves. Therapeutic ultrasound in physical therapy is alternating compression and rarefaction of sound waves with a frequency of 0.7 to 3.3 ...
Low-intensity pulsed ultrasound (LIPUS) is a technology that can be used for therapeutic purposes. It exploits low intensity and pulsed mechanical waves in order to induce regenerative and anti-inflammatory effects on biological tissues, such as bone, [ 1 ] cartilage, and tendon. [ 2 ]
Typical diagnostic ultrasound machines operate in the frequency range of 2-18 megahertz, whereas home ultrasound machines and therapeutic ultrasound machines operate in the frequency range of .7-3.3 megahertz. Diagnostic sonography is typically used to create an audio "image", such as during pregnancy to visualize the developing baby.
Medical ultrasound includes diagnostic techniques (mainly imaging techniques) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints, blood vessels, and internal organs, to measure some characteristics (e.g., distances and velocities) or to generate an informative audible sound.
Ultrasound has been used a cancer therapy since the 1930s. [4] Initially, high-intensity beams were used to heat and destroy cells. Separately, contrast agents were injected prior to ultrasound, which then destroyed nearby cells. However, heat can harm healthy cells as well as cancer cells, and contrast agents work for only a few tumors.
The mechanism of action for sonodynamic therapy is the use of low-intensity ultrasound through the use of focused mechanical waves to create a cytotoxic effect. However, SDT itself is non-thermal, non-toxic, and is able to non-invasively penetrate deep into tissue compared to other delivery methods such as photodynamic therapy.
Gene therapy using ultrasound and microbubbles is also being investigated for ocular disease. [25] In cardiovascular disease, for example, the efficiency of gene therapy can be improved by ultrasound targeted microbubble destruction where a gene-loaded microbubble can be burst to release its contents. [26]
As an ultrasound acoustic wave cannot propagates through the compressive tissue, such as rubber, human tissues part of it and the ultrasound energy will be turned to converted as heat, with focused beams, a very small region of heating can be achieved the part of shallow deep in tissues (usually on the order of 2~3 millimeters).