Search results
Results From The WOW.Com Content Network
The effect of the developmental toxicants depends on the type of substance, dose, duration, and time of the exposure. The first few weeks of embryogenesis in humans is more susceptible to these agents. The embryogenesis is the most crucial time for the action of any teratogenic substances to result in birth defects.
Infants with fetal hydantoin syndrome can benefit from early developmental intervention to ensure that affected children reach their potential. Affected children may benefit from occupational, physical and speech therapy. Various methods of rehabilitative and behavioral therapy may be beneficial.
Teratogens are classified in four main categories: Drugs in pregnancy – in addition to environmental chemicals, includes recreational drug use and pharmaceutical drugs. Vertically transmitted infections; Radiation, such as X-rays; Mechanical forces, such as oligohydramnios; Teratogens affect the fetus by various mechanism including:
Several inhalational anesthetic agents are used in dentistry, e.g., isoflurane, sevoflurane, desflurane, and halothane. [11] The most concerning from the point of view of its health impact, however, is nitrous oxide, an inhalation sedative commonly used in dentistry, particularly for children.
While this is still part of the teratological evaluation procedures today, the field of Teratology is moving to a more molecular level, seeking the mechanism(s) of action by which these agents act. One example of this is the use of mammalian animal models to evaluate the molecular role of teratogens in the development of embryonic populations ...
Examples of minor anomalies can include curvature of the fifth finger (clinodactyly), a third nipple, tiny indentations of the skin near the ears (preauricular pits), shortness of the fourth metacarpal or metatarsal bones, or dimples over the lower spine (sacral dimples). Some minor anomalies may be clues to more significant internal abnormalities.
Teratogens are substances that may cause birth defects via a toxic effect on an embryo or foetus. Wikimedia Commons has media related to Teratogens . See also the categories Carcinogens and Mutagens
Tetracycline use should be avoided in pregnant or lactating women, and in children with developing teeth because they may result in permanent staining (dark yellow-gray teeth with a darker horizontal band that goes across the top and bottom rows of teeth), and possibly affect the growth of teeth and bones.