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The Dota series includes four games that are centered around competitive, online multiplayer gameplay. The original version, Defense of the Ancients, is a community-created Warcraft III custom map developed with the Warcraft III World Editor that was first released in 2003. [1]
[11] [14] Other mapmakers produced Defense of the Ancients spinoffs that added new heroes, items, and features. Among the DotA variants created in the wake of Eul's map was DotA Allstars, originally created and developed by custom map makers Meian and Ragn0r, who took the most popular heroes and compiled them into one map. [11]
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The International (TI) is an annual esports world championship for the five-on-five video game Dota 2.Produced by the game's developer Valve, the International is the final event of the Dota Pro Circuit (DPC) and consists of 20 teams: 12 based on final results from the DPC; six from North America, South America, Southeast Asia, China, Eastern Europe, and Western Europe regional leagues; and ...
Dota Auto Chess is a strategy video game mod for the video game Dota 2. ... Each item has unique effects and some can be combined to form stronger versions. [1]
DOTA-TATE can be reacted with the radionuclides gallium-68 (T 1/2 = 68 min), lutetium-177 (T 1/2 = 6.65 d) and copper-64 (T 1/2 = 12.7 h) to form radiopharmaceuticals for positron emission tomography (PET) imaging or radionuclide therapy. 177 Lu DOTA-TATE therapy is a form of peptide receptor radionuclide therapy (PRRT) which targets ...
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DOTA is derived from the macrocycle known as cyclen.The four secondary amine groups are modified by replacement of the N-H centers with N-CH 2 CO 2 H groups. The resulting aminopolycarboxylic acid, upon ionization of the carboxylic acid groups, is a high affinity chelating agent for di- and trivalent cations.