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As the negative feedback of estrogen is inhibited, the hypothalamus secretes GnRh which in turn stimulates the anterior pituitary to secrete LH and FSH which help in ovulation. Between 60 and 85% of women, mostly with polycystic ovary syndrome (PCOS), ovulate successfully in response to clomiphene with a cumulative pregnancy rate of 30 to 40%.
EE/CPA is used as a combined birth control pill to prevent ovulation and pregnancy in women. [2] It is also approved and used to treat androgen-dependent conditions in women such as acne , seborrhea , hirsutism , female pattern hair loss , and hyperandrogenism due to polycystic ovary syndrome .
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. [1] For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women. [2] There are also recombinant ...
[215] [216] [217] Accordingly, progestogens, both endogenous and exogenous (i.e., progestins), have antigonadotropic effects, [218] and progestogens in sufficiently high amounts can markedly suppress the body's normal production of progestogens, androgens, and estrogens as well as inhibit fertility (ovulation in women and spermatogenesis in men ...
Image credits: Ludwig_Vista2 #7. Endometriosis (tissue from the womb) is not cancer. But it can send out cells that spread through your internal organs and grow, stick your guts together or block ...
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