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For example, if several physicians are asked to score the results of a CT scan for signs of cancer progression, we can ask how consistent the scores are to each other. If the truth is known (for example, if the CT scans were on patients who subsequently underwent exploratory surgery), then the focus would generally be on how well the physicians ...
An additional reason that the chi-squared distribution is widely used is that it turns up as the large sample distribution of generalized likelihood ratio tests (LRT). [8] LRTs have several desirable properties; in particular, simple LRTs commonly provide the highest power to reject the null hypothesis ( Neyman–Pearson lemma ) and this leads ...
Most frequently, t statistics are used in Student's t-tests, a form of statistical hypothesis testing, and in the computation of certain confidence intervals. The key property of the t statistic is that it is a pivotal quantity – while defined in terms of the sample mean, its sampling distribution does not depend on the population parameters, and thus it can be used regardless of what these ...
The AST/ALT ratio or De Ritis ratio is the ratio between the concentrations of two enzymes, aspartate transaminase (AST) and alanine transaminase, aka alanine aminotransferase (ALT), in the blood of a human or animal. It is used as one of several liver function tests, and measured with a blood test.
[135] [136] [137] The virus may also enter the bloodstream from the lungs and cross the blood–brain barrier to gain access to the CNS, possibly within an infected white blood cell. [134] Tropism and multiple organ injuries in SARS-CoV-2 infection. Research conducted when Alpha was the dominant variant has suggested COVID-19 may cause brain ...