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  2. Sporulation in Bacillus subtilis - Wikipedia

    en.wikipedia.org/wiki/Sporulation_in_Bacillus...

    The wrong decision can be catastrophic: a vegetative cell will die if the conditions are too harsh, while bacteria forming spores in an environment which is conducive to vegetative growth will be out competed. [3] In short, initiation of sporulation is a very tightly regulated network with numerous checkpoints for efficient control. [citation ...

  3. Insulin-like growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_1

    Cyclic glycine-proline (cGP) is a metabolite of hormone insulin-like growth factor-1 (IGF-1). It has a cyclic structure, lipophilic nature, and is enzymatically stable which makes it a more favourable candidate for manipulating the binding-release process between IGF-1 and its binding protein, thereby normalising IGF-1 function. [16]

  4. Insulin-like growth factor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor

    Insulin-like growth factor 2 (IGF-2, at times IGF-II) is thought to be a primary growth factor required for early development while IGF-1 expression is required for achieving maximal growth. Gene knockout studies in mice have confirmed this, though other animals are likely to regulate the expression of these genes in distinct ways.

  5. Insulin-like growth factor 1 receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor...

    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1 ...

  6. Insulin-like growth factor-binding protein - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor...

    IGF-1 binds to IGFBP-3 in a 1:1 molar ratio. IGF-BP also binds to IGF-1 inside the liver, allowing growth hormone to continuously act upon the liver to produce more IGF-1. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology with each other and have binding affinities for IGF-I and IGF-II at the same ...

  7. Bacillus subtilis - Wikipedia

    en.wikipedia.org/wiki/Bacillus_subtilis

    Bacillus subtilis (/ b ə ˈ s ɪ l. ə s s u b ˈ t iː. l i s /), [3] [4] known also as the hay bacillus or grass bacillus, is a gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants, humans and marine sponges.

  8. Bacterial growth - Wikipedia

    en.wikipedia.org/wiki/Bacterial_growth

    The measurement of an exponential bacterial growth curve in batch culture was traditionally a part of the training of all microbiologists; the basic means requires bacterial enumeration (cell counting) by direct and individual (microscopic, flow cytometry [1]), direct and bulk (biomass), indirect and individual (colony counting), or indirect ...

  9. Endospore - Wikipedia

    en.wikipedia.org/wiki/Endospore

    Bacteria produce a single endospore internally. The spore is sometimes surrounded by a thin covering known as the exosporium, which overlies the spore coat. The spore coat, which acts like a sieve that excludes large toxic molecules like lysozyme, is resistant to many toxic molecules and may also contain enzymes that are involved in germination.