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Initially, multivitamins were designed to respond to widespread nutritional deficiencies. [49] These supplements were seen as a practical solution to combat malnutrition, improving public health by providing vital nutrients that were otherwise scarce. As the 20th century progressed, the use of multivitamins expanded beyond addressing deficiencies.
Multivitamins divorced from foods became a commercial product in the 1940s, and Americans now spend $8 billion per year on the supplements. There are some cases where vitamin pills can be helpful ...
Supplemental vitamin E significantly reduced elevated liver enzymes, steatosis, inflammation and fibrosis, suggesting that the vitamin may be useful for treatment of nonalcoholic fatty liver disease (NAFLD) and the more extreme subset known as nonalcoholic steatohepatitis (NASH) in adults, [96] [97] [98] but not in children. [99] [100]
The body's stores for different vitamins vary widely; vitamins A, D, and B 12 are stored in significant amounts, mainly in the liver, [20] and an adult's diet may be deficient in vitamins A and D for many months and B 12 in some cases for years, before developing a deficiency condition.
There is no association between regular intake of multivitamins and a lower risk of death, according to a two-decade National Institutes of Health study that involved nearly 400,000 adults from ...
Blood tests are performed to rule out other causes and to confirm an elevated level of vitamin B 6 with an absence of hypophosphatasia. [ 14 ] [ 11 ] [ 12 ] [ 57 ] [ 58 ] Examination does not typically show signs of a motor deficit , dysfunction of the autonomic nervous system or impairment of the central nervous system , [ 4 ] [ 3 ] although ...