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Catabolite Activator Protein (blue) bound to a piece of DNA (red). In cell biology, catabolite activator protein (CAP), which is also known as cAMP receptor protein (CRP), is a trans-acting transcriptional activator in bacteria that effectively catalyzes the initiation of DNA transcription by interacting with RNA polymerase in a way that causes the DNA to bend.
In 2013, Batut et al. [13] combined CAP trapper, template switching, and 5′-phosphate-dependent exonuclease digestion in RAMPAGE to maximize promoter specificity. In 2014, Murata et al. [ 14 ] published the nAnTi-CAGE protocol, where capped 5′ ends are sequenced on the Illumina platform with no PCR amplification and no tag cleavage.
Molecular Operating Environment (MOE) is a drug discovery software platform that integrates visualization, modeling and simulations, as well as methodology development, in one package. MOE scientific applications are used by biologists, medicinal chemists and computational chemists in pharmaceutical, biotechnology and academic research.
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Anatomical pathology (Commonwealth) or anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
The Association for Molecular Pathology is a 501(c)(3) non-profit scientific society that advances the clinical practice, science, and excellence of molecular and genomic laboratory medicine through education, innovation, and advocacy to enable the highest quality health care.
The origins of the ISMB conference lie in a workshop for artificial intelligence researchers with an interest in molecular biology held in November 1991. [3] The workshop was organised by American researcher Lawrence Hunter, then director of the Machine Learning Project at the United States National Institutes of Health's National Library of Medicine (NLM) in Bethesda, Maryland. [4]
The structures of CaP and sodium peroxide (Na 2 O 2) are very similar. [1] The solid is described as a salt: (Ca 2+) 2 P 2 4−, or Ca 2 P 2.Since the bonding is ionic, the diphosphide centers carry negative charge and are easily protonated.