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Leukoplakia is, therefore, the most common premalignant lesion that occurs in the mouth. [41] Leukoplakia is more common in middle-aged and elderly males. [30] The prevalence increases with increasing age. [2] In areas of the world where smokeless tobacco use is common, there is a higher prevalence. [2]
Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised , especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS).
Erythroplakia is analogous to the term leukoplakia which describes white patches. Together, these are the 2 traditionally accepted types of premalignant lesion in the mouth, [9] [10] When a lesion contains both red and white areas, the term "speckled leukoplakia" or "eyrthroleukoplakia" is used.
Hairy tongue may be confused with hairy leukoplakia, however the latter usually occurs on the sides of the tongue and is associated with an opportunistic infection with Epstein–Barr virus on a background immunocompromise (almost always human immunodeficiency virus infection but rarely other conditions which suppress the immune system). [6]
Hairy leukoplakia (oral hairy leukoplakia) Intraoral dental sinus; Linea alba; Leukoplakia; Leukoplakia with tylosis and esophageal carcinoma; Major aphthous ulcer (periadenitis mucosa necrotica recurrens) Median rhomboid glossitis (central papillary atrophy) Melanocytic oral lesion; Melkersson–Rosenthal syndrome
Leukoplakia - can affect the tongue Tongue coating - food debris, desquamated epithelial cells and bacteria often form a visible tongue coating. [ 7 ] This coating has been identified as a major contributing factor in bad breath ( halitosis ), [ 7 ] which can be managed by brushing the tongue gently with a toothbrush or using special oral ...
Diagnosis is mainly clinical, based on the history and clinical appearance. The differential diagnosis includes other oral white lesions such as Leukoplakia, squamous cell carcinoma, oral candidiasis, lichen planus, white sponge nevus and contact stomatitis. [7] In contrast to pseudomembraneous candidiasis, this white patch cannot be wiped off. [7]
Oral hairy leukoplakia; Pulmonary tuberculosis (TB) diagnosed in last two years; Severe presumed bacterial infections (e.g. pneumonia, empyema, meningitis, bacteraemia, pyomyositis, bone or joint infection) Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis; Conditions where confirmatory diagnostic testing is necessary ...