Ads
related to: mucosal barrier immunology lab
Search results
Results From The WOW.Com Content Network
Mucosal immunology is the study of immune system responses that occur at mucosal membranes of the intestines, the urogenital tract, and the respiratory system. [1] The mucous membranes are in constant contact with microorganisms , food, and inhaled antigens . [ 2 ]
In 2002, Făgărășan was appointed leader of the Riken Laboratory for Mucosal Immunity at the Research Centre for Allergy and Immunology. [2] Făgărășan looks to understand the mechanisms between the microbiota and the immune system at the mucosal barrier. [3]
The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the intestinal mucosa that ensures adequate containment of undesirable luminal contents within the intestine while preserving the ability to absorb nutrients. The separation it provides between the body and the gut prevents the uncontrolled ...
In 2003, she completed a certificate in periodontics at the University of Maryland School of Dentistry where she completed a PhD in immunology in 2006 in the department of diagnostic sciences and pathology. [1] [2] Her dissertation was titled Dissection of factors contributing to HIV susceptibility in mucosal associated lymphoid tissues. [3]
The barrier formed by the intestinal epithelium separates the external environment (the contents of the intestinal lumen) from the body [6] and is the most extensive and important mucosal surface of the body. [7]
Kronenberg also has research in mucosal immunology and on the development of inflammatory bowel diseases. Kronenberg's work had a major impact in defining how glycolipid antigens are taken into cells and processed in lysosomes [9] and unraveled the intracellular traffic of CD1d, [10] which is the MHC class I molecule that presents lipid antigens.
Intraepithelial lymphocytes (IEL) are lymphocytes found in the epithelial layer of mammalian mucosal linings, such as the gastrointestinal (GI) tract and reproductive tract. [1] However, unlike other T cells, IELs do not need priming. Upon encountering antigens, they immediately release cytokines and cause killing of infected target cells.
Mucosal-associated invariant T cells (MAIT cells) make up a subset of T cells in the immune system that display innate, effector-like qualities. [ 1 ] [ 2 ] In humans, MAIT cells are found in the blood, liver, lungs, and mucosa , defending against microbial activity and infection. [ 1 ]