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Latent tuberculosis (LTB), also called latent tuberculosis infection (LTBI) is when a person is infected with Mycobacterium tuberculosis, but does not have active tuberculosis (TB). Active tuberculosis can be contagious while latent tuberculosis is not, and it is therefore not possible to get TB from someone with latent tuberculosis.
[1] [9] People with latent TB do not spread the disease. [1] Active infection occurs more often in people with HIV/AIDS and in those who smoke. [1] Diagnosis of active TB is based on chest X-rays, as well as microscopic examination and culture of bodily fluids. [10] Diagnosis of latent TB relies on the tuberculin skin test (TST) or blood tests ...
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
TB infection No disease: Positive reaction to tuberculin skin test Negative bacteriologic studies (if done) No clinical, bacteriologic, or radiographic evidence of TB 3: TB, clinically active: M. tuberculosis cultured (if done) Clinical, bacteriologic, or radiographic evidence of current disease 4: TB Not clinically active: History of episode(s ...
Chest x-ray of Ghon's complex of active tuberculosis. Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. [1] [2] The lesions consist of a Ghon focus along with pulmonary lymphadenopathy within a nearby pulmonary lymph node.
The exact prevalence of tuberculous lymphadenitis varies between countries and regions, with higher rates seen in developing countries. [1] [3] [5] Studies have shown that women may have higher rates of tuberculous lymphadenitis compared to men. [1] Conversely, men appear to have higher rates of pulmonary tuberculosis. [1]
In a recently published metaanalysis, [26] with data from both developed and developing countries, QuantiFERON-TB Gold In Tube had a pooled sensitivity for active TB of 81% and specificity of 99.2%, whereas T-SPOT.TB had a pooled sensitivity of 87.5% and specificity of 86.3%. In head-to-head comparisons, the sensitivity of IGRAs surpassed TST.
Symptomatic infections are apparent and clinical, whereas an infection that is active but does not produce noticeable symptoms may be called inapparent, silent, subclinical, or occult. An infection that is inactive or dormant is called a latent infection. [54] An example of a latent bacterial infection is latent tuberculosis.