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Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about three people per million members of the population. [1] It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. [ 2 ]
Singer Jimmy Buffett died of Merkel cell carcinoma, a rare skin cancer, in September. Here’s what to know about the cancer, including symptoms and treatment.
As with all skin cancers, sun exposure is a risk factor, as is a compromised immune system and previous history of skin cancer.
Cancer Research UK has recently warned that skin cancer cases are set to rise by half by 2040
Other modalities of treatment such as photodynamic therapy, epidermal radioisotope therapy, [61] topical chemotherapy, electrodesiccation and curettage can be found in the discussions of basal-cell carcinoma and squamous-cell carcinoma. Mohs' micrographic surgery (Mohs surgery) is a technique used to remove the cancer with the least amount of ...
The US Food and Drug Administration (FDA) approved it in March 2017, for the treatment of Merkel-cell carcinoma, [85] an aggressive type of skin cancer. The EMA approved it in September 2017, for the same indication. [87] This is the first FDA-approved treatment for metastatic Merkel-cell carcinoma, a rare, aggressive form of skin cancer. [85]
Merkel cell carcinoma accounts for fewer than 1% of all skin cancers — but when it metastasizes it often turns deadly. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please ...
Merkel cells, also known as Merkel–Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates. They are abundant in highly sensitive skin like that of the fingertips in humans , and make synaptic contacts with somatosensory afferent nerve fibers .