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Chloroquine (CQ) then becomes protonated (to CQ 2+), as the digestive vacuole is known to be acidic (pH 4.7); chloroquine then cannot leave by diffusion. Chloroquine caps hemozoin molecules to prevent further biocrystallization of heme, thus leading to heme buildup. Chloroquine binds to heme (or FP) to form the FP-chloroquine complex; this ...
A feline zoonosis is a viral, bacterial, fungal, protozoan, nematode or arthropod infection that can be transmitted to humans from the domesticated cat, Felis catus.Some of these diseases are reemerging and newly emerging infections or infestations caused by zoonotic pathogens transmitted by cats.
More than 800 species of bacteria colonize oral mucus, 1,300 species are found in the gingival crevice, and nearly 1,000 species comprise dental plaque. The mouth is a rich environment for hundreds of species of bacteria since saliva is mostly water and plenty of nutrients pass through the mouth each day.
Feline disease refers to infections or illnesses that affect cats. They may cause symptoms, sickness or the death of the animal. Some diseases are symptomatic in one cat but asymptomatic in others. Feline diseases are often opportunistic and tend to be more serious in cats that already have concurrent sicknesses.
Fusobacterium is a genus of obligate anaerobic, Gram-negative, [2] non-sporeforming bacteria [3] belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. [ 4 ] [ 5 ] Fusobacterium was discovered in 1900 by Courmont and Cade and is common in the flora of humans.
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Lentigo in cats is a common dermatological condition characterized by the presence of small, flat, brownish spots on the skin — particularly around the lips, nose, and eyelid margins.
F. nucleatum has a demonstrated association with colorectal cancer. Fusobacterium species have been found at higher quantities in certain types of colon tumors than in surrounding colon tissue or the colons of healthy individuals, but whether this is an indirect correlation or a causal link is unclear.