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Hemoglobin Portland II (also referred to as ζ 2 β 2 or HbE Portland-2) is a form of hemoglobin existing at low levels during embryonic and fetal life, composed of two zeta chains and two beta chains.
A human peripheral blood smear; NRBCs are visible as larger cells with dark centers.. A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus.
An increase in the number of white blood cells in circulation is called leukocytosis. [18] This increase is most commonly caused by inflammation. [18] There are four major causes: increase of production in bone marrow, increased release from storage in bone marrow, decreased attachment to veins and arteries, decreased uptake by tissues. [18]
Conventionally, a leukocytosis exceeding 50,000 WBC/mm 3 with a significant increase in early neutrophil precursors is referred to as a leukemoid reaction. [2] The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature neutrophil precursors, in contrast to the immature forms typically seen in acute leukemia.
Spherocytosis is the presence of spherocytes in the blood, i.e. erythrocytes (red blood cells) that are sphere-shaped rather than bi-concave disk shaped as normal.. Spherocytes are found in all hemolytic anemias to s
Fetal viability is the ability of a human fetus to survive outside the uterus.Viability depends upon factors such as birth weight, gestational age, and the availability of advanced medical care.
The white blood cell differential is a common blood test that is often ordered alongside a complete blood count.The test may be performed as part of a routine medical examination; to investigate certain symptoms, particularly those suggestive of infection or hematological disorders; [5] [6] or to monitor existing conditions, such as blood disorders and inflammatory diseases.
Howell–Jolly bodies: small, round inclusions seen in erythrocytes (peripheral blood – MGG stain) This DNA appears as a basophilic (purple) spot on the otherwise eosinophilic (pink) erythrocyte on a standard H&E stained blood smear.