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Heat stroke is an acute temperature elevation caused by exposure to excessive heat, or combination of heat and humidity, that overwhelms the heat-regulating mechanisms of the body. The latter is a relatively rare side effect of many drugs, particularly those that affect the central nervous system .
Photothermal Therapy, use of infrared radiation to treat cancer; Thermotherapy, use of heat for treating other conditions; Coley's toxins, a bacteria mixture used to generate fevers as an alternative cancer treatment; Tronado machine, a device that uses microwave radiation to generate hyperthermia for cancer (no evidence of benefit)
Plasma, often called the fourth state of matter, is an ionized gas containing positive ions and negative ions or electrons, but is approximately charge neutral on the whole. The plasma sources used for plasma medicine are generally low temperature plasmas, and they generate ions, chemically reactive atoms and molecules, and UV-photons.
As in other mammals, human thermoregulation is an important aspect of homeostasis. In thermoregulation, body heat is generated mostly in the deep organs, especially the liver, brain, and heart, and in contraction of skeletal muscles. [1] Humans have been able to adapt to a great diversity of climates, including hot humid and hot arid.
Bags of frozen plasma, from a person with hypercholesterolemia (left) and typical plasma (right) Plasma is normally yellow due to bilirubin, carotenoids, hemoglobin, and transferrin. [18] In abnormal cases, plasma can have varying shades of orange, green, or brown. The green color can be due to ceruloplasmin or sulfhemoglobin.
The start of heat stroke can be sudden or gradual. [3] Heatstroke is a life-threatening condition due to the potential for multi-organ dysfunction, [6] with typical complications including seizures, rhabdomyolysis, or kidney failure. [3] Heat stroke occurs because of high external temperatures and/or physical exertion.
In humans, CD27 is a good marker for plasma cells; naïve B cells are CD27−, memory B-cells are CD27+ and plasma cells are CD27++. [5] The surface antigen CD138 (syndecan-1) is expressed at high levels. [6] Another important surface antigen is CD319 (SLAMF7). This antigen is expressed at high levels on normal human plasma cells.
Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock , [ 1 ] but are now known to also be expressed during other stresses including exposure to cold, [ 2 ] UV light [ 3 ] and during wound healing or tissue remodeling. [ 4 ]